| Puang Amo coffee shop | Kafe | Jl. Perintis Kemerdekaan No.1 kel | Sen–Jum 07.00–23.00 |
| Puri Kitchen | Pemasok makanan dan minuman katering | Jl. Samratulangi | Sen–Sab 09.00–22.00 |
| Puskesmas Oesapa | Pusat kesehatan masyarakat | Village, Jl. Suratim Street, RT.15/RW.06 | Sen–Jum 07.30–15.00 |
| Rationstore_ | Toko aksesori pakaian | Jl. Bunga Lontar No.01, RT.11/RW.4 | Sen–Sab 08.00–21.00 |
| Rice Salon | Salon kecantikan | Jl. Perwira walikota No.6 | Sen–Sab 10.00–19.00 |
| Richeese Factory Frans Seda | Restoran | Oesapa Bar., Kec. Klp. Lima, Kota Kupang, Nusa Tenggara Tim. | Setiap hari Buka 24 jam |
| Royal Mobil | Bengkel perawatan bodi mobil | Jl. Nasional Trans-Timor | Sen–Sab 09.00–17.00 |
| RTD | Layanan transportasi | Jl. Nasional Trans-Timor | Sen–Sab 09.00–18.00 |
| Ruby Spa & Spa | Spa | Jalan Flamboyan, RT.06/RW.02 | Sen–Jum 09.00–22.00 |
| Rumah Gigi Kupang | Dokter gigi | Jl. Sam Ratulangi 5 No.8 | Sen–Jum 15.00–19.00 |
| Rumah Makan Tanjung | Restoran seafood | Jl. Nasional Trans-Timor No.126A | Sen–Kam 08.00–14.30, 18.15–21.30 |
| Rumah Sakit Hewan Kupang | Toko hewan peliharaan | Jl. Nasional Trans-Timor No.Km No.7 | Sen–Kam 07.30–16.00 |
| Sadajiwa Oto Service | Bengkel mobil | Samping Neo Aston, Jl. Piet A. Tallo | Sen–Sab 08.30–18.00 |
| Salome GeGe | Toko makanan sehat | Depan Hemart | Setiap hari 10.00–22.00 |
| Salome Smpn 5 kupang | Kedai sarapan & makan siang | Jl. Frans Seda | Sen–Jum 09.00–19.40 |
| Salon Eleanor | Salon kecantikan | Jl. Piet A. Tallo | Setiap hari 08.30–19.30 |
| Saran Meraih Sukses. PT | Toserba | Jalan Timor Raya No No.Km. 9 | Sen–Jum 08.00–18.00 |
| Sayur Pertigaan | Toko | Lasiana, Kec. Klp. Lima, Kota Kupang, Nusa Tenggara Tim. 85228 | Sen–Sab 08.00–23.00 |
| SC | Tempat fitness | Lasiana, Kec. Klp. Lima, Kota Kupang, Nusa Tenggara Tim. | Sen–Jum 09.00–17.00 |
| Se'i Babi Mas Bro | Toko makanan | Oesapa, Kec. Klp. Lima, Kota Kupang, Nusa Tenggara Tim. 85228 | Setiap hari 10.00–21.00 |
| Seafood Suka Ramai | Restoran seafood | Jl. Piet A. Tallo | Sen–Sab 10.00–23.00 |
| Service radiator pohon duri Oesapa | Komplek perumahan | Jl. Nasional Trans-Timor No.km.08 | Sen–Sab 07.00–05.00 |
| Shinta Variasi Motor | Toko suku cadang motor | Jl. Nasional Trans-Timor No.96A KM. 6 | Sen–Sab 08.00–18.00 |
| Showroom Tirosa | Dealer mobil bekas | Jl. Nasional Trans-Timor | Sen–Sab 08.00–19.00 |
| Silmen SKETSA | Lukisan | Jl. Hans Kapitan | Sen–Jum Buka 24 jam |
| Sinar mobil | Bengkel mobil | belakang sorum hanamurah, Jl. Nasional Trans-Timor No.km 06 | Sen–Sab 08.00–18.00 |
| Smilelux Dental Care (Praktek Dokter Gigi) | Klinik gigi | Jl. Bunda Hati Kudus | Sen–Sab 09.00–21.00 |
| SONYA Foods | Pemasok makanan dan minuman katering | Jl. B. Pandie No.28 | Sen–Jum 11.00–22.30 |
| SPC Oesapa | Toko ponsel | Jl. Nasional Trans-Timor | Sen–Sab 09.00–21.00 |
| Station Aki Eltari | Toko aki mobil | Jl. Frans Seda No.88 Blok A | Sen–Sab 08.00–18.00 |